Disc4All Publications

  • No evidence of association between either Modic change or disc degeneration and five circulating inflammatory proteins

    Abstract Introduction Intervertebral disc degeneration and Modic change are the main spinal structural changes associated with chronic low back pain (LBP). Both conditions are thought to manifest local inflammation and if inflammatory proteins translocate to the blood circulation could be detected systemically. The work here assesses whether the presence of disc degeneration is associated with detectable blood level changes of five inflammatory markers and whether chronic LBP is associated with these changes.

    Roger Compte, Maxim B. Freidin, Isabelle Granville Smith, Christine L. Le Maitre, Dovile Vaitkute, Ayrun Nessa, Genevieve Lachance, Frances M. K. Williams

  • PREDICTING GENE DISEASE ASSOCIATIONS WITH KNOWLEDGE GRAPH EMBEDDINGS FOR DISEASES WITH CURTAILED INFORMATION

    Francesco Gualdi, Baldomero Oliva, Janet Piñero

  • Semi-automatic Assessment of Facet Tropism from Lumbar Spine MRI using Deep Learning: A Northern Finland Birth Cohort Study

    Kowlagi, Narasimharao Msca; Kemppainen, Antti PhDb; Panfilov, Egor Msca; McSweeney, Terence MSca; Saarakkala, Simo PhDa,b; Nevalainen, Mika MD, PhDa,b; Niinimäki, Jaakko MD, PhDb; Karppinen, Jaro MD, PhDa,c; Tiulpin, Aleksei PhDa,d

  • The Interplay between Biochemical Mediators and Mechanotransduction in Chondrocytes: Unravelling the Differential Responses in Primary Knee Osteoarthritis

    Maria Segarra-Queralt, Katherine Crump, Andreu Pascuet-Fontanet, Benjamin Gantenbein, Jérôme Noailly